Epigenetic transformation — you are what your grandparents ate: Pamela Peeke at TEDxLowerEastSide

Epigenetic transformation — you are what your grandparents ate: Pamela Peeke at TEDxLowerEastSide


Translator: Rhonda Jacobs
Reviewer: Peter van de Ven So the hero’s journey
is all about transformation, isn’t it? We’re transforming
throughout the entire journey, whether it’s departure,
initiation or return. You know, it’s interesting, in initiation,
which is what I’m talking about, Joseph Campbell made it very clear: It’s war out there! It’s hell. And you need to be armed
with everything you can possibly find to be able to get through it,
day by day, minute by minute, nanosecond by nanosecond. Now, the transformation you’ve heard about
could be mental, psychological, spiritual. But I’m going to teach you, I’m going to guide you through
a brand new kind of transformation based upon a science that’s so exciting that’s it’s blown the minds
of people like myself, a physician and a scientist,
and all my colleagues. And now I’m going to blow your mind. Are you ready? (Audience) Yeah! Have you ever heard of epigenetics? Raise your hand. Okay, very good. Excellent. Have you had your kale today? Soon, soon, you’ll understand
why this is such – well – an epigenetic transformation. A tale of kale. (Laughter) Ready? Okay. Well, made it very simple. First, we start with this: I was taught, and I’m going
to teach you my journey too, share it with you, that you are what you eat. Have you heard this? Of course! You are what you eat. So, you know, out there,
sometimes it works; well, sometimes it doesn’t. (Laughter) I try, and I really do. So, I try to live
a very healthy lifestyle. There’s my armpit picture. I am a triathlete; I like to get out there and, you know,
get outdoors at any excuse I can, no matter what it looks like when I do it. But I do it. I have fun. I show up. The same thing goes with the food. Lots of colors – check! check! check! They tell me what to do – I do it! That’s exactly what I love to do, right? Did you do that too? Of course you did. Everything was going well, until something
rather interesting happened. Well, you see, the holy grail, all along,
was DNA was your destiny, and that, quite frankly,
genes controlled you. So, you are what you are, you know? Whatever you got when you were born,
you’re stuck with! And that’s it! A little proclivity toward obesity,
toward diabetes, heart disease, ruh roh, you’re in trouble. Right? What could you do about it? Well, you kind of just keep remembering, “Well, I am what I eat.
I try to do the best I can.” But as scientists, we never knew
where any of this was going. We had some observational studies,
and back and forth. What was really happening
in that black box? And then all hell broke out in 2007. That’s how recent it was. The birth of epigenetics. Let me tell you how it happens. I’ll bet you think that all great science
happens with strategy, and we sit down with blueprints
and figure this out right off the bat. Nah. We’re just screwing around in the lab just trying to figure out
fun things to do. And then one day,
something wild and crazy happens. Dr. Randy Jirtle at Duke University one day was playing around
with some very special mice – they’re called Agouti mice. Now, Agouti mice have
the Agouti gene, appropriately so. Now, this gene basically condemns them to a life of being obese, floppy, yellow – very important because
that’s connected with this gene – color of the fur, and they die early
of all the usual suspects: heart diesease, diabetes and cancer. Kind of a – not a good life. Right? So one day, he was saying, “You know,
I know where this gene’s located. And I also know that there are these
funny little things called methyl donors – CH3, a little side chain – that we could, you know,
sometimes play with here, that might just do something
with this gene … I don’t know. Well, what’s the worst that can happen?” So how do we give
these little happy campers, these Agouti mice, methyl donors? You guessed it: It’s the green stuff. Mom was right. So, he fed them all the greens he could
in the form of folate and B vitamins, a little greens, he kind of
ground them all up, and said, “Here.” And he fed the mothers
who were going to become pregnant. And then he sat around, and he thought,
“Well, I wonder what’s going to happen.” You see, we scientists
have no personal life, so we sit around looking at cages,
waiting for mice to be born. This is what we do on Friday nights. Right? So he’s sitting there like this
with the whole team, going, “Okay, let’s just
pop one of those little babes out and see what it looks like.” Son of a gun. The birth of epigenetics. Only eating greens, that mother
produced a baby that was lean, brown and lived forever. (Laughter) How cool is that? (Laughter) Eating your greens. Well, needless to say, this was published, and this absolutely ripped apart
the entire scientific world. What?! This is heresy! DNA is not destiny? No. As it turns out, everything you do
with your whole life is now your destiny. Everything from eating
to thoughts that you may have to every single lifestyle habit is messing with one thing in particular. And what that is, is your very gene expression. This is a picture from my laboratory
at the National Institutes of Health. These are fat cells – “Know thy enemy.” So – (Laughter) This is important –
it’s like a therapy thing. Just keep staring at it,
and maybe it will just go away after – But there it is. And you can see
all the way into the nucleus. Right? And one of the things we found out was, wow, I can affect everything
from my fat cell distribution to how many I have. I could reverse it. So if I got born with something
that was a little funky, I can dampen that down. Did you know that if you were born with the most lethal form
of the obesity gene, the FTO gene, that by doing something
as simple as taking a walk every day, over the course of six months,
you dampen it by 40 percent. Add that – add a little kale to it – (Laughter) and then what happens? Wow, you’re way over 50 percent. We’re loving it. This is good!
We didn’t know this! Every single thing. That means, for instance, addiction. Let’s look at that for a moment. Cigarettes. Like to smoke? This is your last day. (Laughter) Because what happens is
over the course of two to three years, we have counted over 50,000
different genetic mutations that come out of this, variations on your gene expression, because you smoked. Your body’s saying, “What?
What are you doing?! Think about this!” Well, who’s saying that, actually? Let’s go down to the gene level. When you go to the actual
gene level, what do you see? You see the gene sitting there.
Nothing’s going on with the gene. The gene’s just sitting there
with lots of potential. Little histones hang around,
they’re little proteins, and they basically monitor
what’s going on. They play with the volume
on this whole thing. And they basically, “What are you doing?!
You’re eating a what?! That’s a Ho-Ho! That’s not food.
That’s a science fair project! (Laughter) I can’t believe you just
put that in your mouth! Okay, fine! Suffer!” And then, all of the sudden, the speech to the rest
of the body from that gene is “Erode immune function.” Here come some allergens.
It’s just a mess. (Gasp) “She ate an apple! Yay!” And the histones
are all having little orgasms. And they’re all happy and everything. And then they, “Whoa! …” And then you augment immune function. You rock and roll. You fill your body with phytonutrients. Isn’t that the way to go? What if you were born
with the addictive gene? You can dampen it; you can quiet it by every mouthful that you take, every step that you take
with physical movement, for instance. And also, please, whatever you do,
don’t forget the brain. Every thought you have. Right now, every single one of you, I’m here as a physician
to save your lives. Don’t you just love that? I love saying that. Makes me feel so – well, anyway. I digress. So what I’d like you to do right now
is I want to save your life a little bit. I want you to turn
to the person next to you, and I want you to say, “You are so cool!”
and give them a high five, right now. (Audience responds) Alright! Okay, we’re done. Now, in those few seconds,
while you were high-fiving somebody – get your hands off her! – (Laughter) what you were doing
was actually changing gene expression. Because you see you laughing right now?
I’m helping save your life. Why? Research shows that you have a choice: You can either laugh or be in despair. You cannot do both at the same time, because the brain doesn’t work that way. So I’m keeping you over here
instead of over there. Are you enjoying yourselves? Wonderful. I’m thrilled. Okay. (Laughter) Now, just want to drill it home again. DNA is not destiny. This is brand new! This is so exciting and so empowering! It’s kind of scary too, isn’t it? Because when you think about it,
every single thought, every mouthful, every single movement that you take
changes gene expression. Remember those histones – they’re scoping you right now – alters your destiny and transforms the mind-body. What’s not to love? So, instead of “You are what you eat,” you are what your parents ate? Well, that’s what this research showed. So, hmm, wait a minute now, in my journey, I had
to think about this for a second. No comment about the hair. (Laughter) I was helpless. (Laughter) Now, there’s my mom and my dad. The good news is they ate well. So I’m looking pretty good
in the neighborhood, right? What if they didn’t?
What if they were, like, trash eaters? I mean, you know, welcome to America. So here’s the deal: What if they were eating not so well? A lot of science fair projects. Hmmm. Am I still okay? Yeah. You know why? Epigenetics works that way too. Here’s the way it works. Remember this. Genetics may load the gun,
but epigenetics pulls the trigger. Ahhh. I see you’re all going, Whew! Wow, you can put the Prozac away;
you’re feeling better. It’s good. It’s good. So, I Iucked out.
My parents were pretty cool. Alright? I’m looking good. And then all of the sudden,
just when I was sitting back, thinking, “Yeah,
this is feeling real good,” new research showed up: You are what your grandparents ate?! Are you kidding me?! That’s two generations. Look, this is a hero’s journey already. I’m working as hard as I can;
I’m trying to do this right. What?! Two generations?!
You’re killing me here. So I started thinking
about this for a second. I know the grandparents
on my mom’s side. They’re okay; they’re exonerated. Ate okay. Musicians. Joyful.
Really nice people. Whatever. Didn’t know my dad’s side, because they died early. And I was wondering, Wow,
who are these people and what goes on? So this is Grandpa Raymond. Right? And this is my grandmother
on that side, my father’s side. And that is Grandma Mollnar. Hmmm. Elizabeth Mollnar. What were you cooking? How did you eat? I started getting a little paranoid. Why? Because the new science,
on top of the Agouti mice, there was something
incredible that came down that you need to understand. You know, we look at nature
and nurture intertwined. A number of studies
showed something really mind-blowing that I want to share with you. And that is, the Swedes
were the lead-off on this. The Swedes love to count
demographics and numbers. Indeed, they collected some of the most
incredible data I’ve ever seen. And this is in the mid-1880s. There’s a wonderful
little place called Överkalix. And in this place –
it’s fairly remote in Sweden – they either had feast or famine. And after looking at multiple generations,
guess what they found. That if you were the child
and the grandchild of someone who had been in famine,
you actually live longer. Because what happens is your genes
kick in with survival, don’t they? All of the sudden, you just sort of
amp it up with the survival thing. That’s the good news. The funky news is you also end up
having other issues like depression. Right? Well, what about if it was feast? You’re sitting around there going,
yeah, give me that remote. And just letting in rip. What happens with those? You actually die earlier, all cause. Hmmm, that’s interesting. What about the horrific issue
of World War II with the Dutch Hongerwinter. And what they did during that time was there were little towns in the Netherlands
that were cut off, that were blockaded during that terrible war. And those people
were eating 580 calories a day. 22,000 people died. What happened to their children
and their grandchildren? They were all very
and significantly underweight for at least two generations, in addition to the psychological prodrom. The industrial revolution.
Hmm, what’s up with that? A lot of plastics. A lot of science fair projects. What do you think that’s done? Hmmm. Could that have laid the groundwork
for a lot of the issues we see today? Question mark. The epigeneticists are hard at work. And then finally, the British Avon study of the mid-1990s. Guess what they found. And this was very important information. When you had the feast or famine, or when you had, in this case, smoking
among men, they looked at specifically. And if the smoking started
between the ages of 9 and 12, during the time when your epigenome
was most vulnerable, guess what happened. Their sons became overweight and obese
and so did their grandchildren. There’s a crossover. Wow. Suddenly, I was thinking,
grandparents, grandparents. Huh. I have to know more about this. I really want to understand more about me. What happened to that side of the family? Because that was a big question mark. So I scoped it out. Guess what. I’m the direct descendant of gypsies! It’s a trip! We have all kinds of Hungarians
and gypsies and wild and crazy people on that side of the family. And that’s what they ate. What is that yellow stuff, anyway? I wanted to understand
what kind of life they lived. Well, as it turns out, it was a joyful,
wild and crazy life too. Just different food. I was kind of interested in that food. Kind of paranoid. Where were the greens
that I learned to love – those little methyl donors? Well, here’s a recipe I found for one of the soups
that my grandmother made. You see where it says kale, right? (Laughter) I’m obsessed! You noticed that. Well, as it turns out,
for crying out loud, you methylate not just with kale – that’s nothing more than a metaphor for all the great things
you’re going to be doing for your body, epigenetically, with
the great thoughts that you had, with movement that you have, everything. And with what you eat,
and that’s all good stuff. But I was still paranoid. I was thinking, hmm, I wonder
what my genes look like. And I don’t mean Calvin Klein. So, I went ahead and got a BodySync
data analysis, a DNA analysis. Guess what I got. A little swab just like
that CSI Miami thing on TV. I went for the swab, sent it off, and I sat around thinking, oh no. And I looked at the whole host of genes. I wanted to make sure
I was methylating optimally. And so would you. So, I looked at one particular gene, especially – I really wanted
to hone in on this one. Because this was a gene
that was really, really, really important to be able to help take methyl donors
from folate, like from kale, and to be able to do DNA repair. With all the crazy things
I do all day long, and you do all day long, I wanted to repair my DNA optimally. So, I looked at this one gene: methylene tetrahydrofolate reductase. That’s the name of it. Well, I’d never seen it in gene-speak. Well, there it is. (Laughter) Okay. I knew you’d get it immediately. (Laughter) I looked at it and I fell off my chair. I said, I can’t put that on a slide. (Laughter) It’s the mother (ahem) gene. (Laughter) And in the case of Grandmother Mollnar,
it’s a – put a G there – it’s a grandmother (ahem) gene. So there it was.
It’s an easy one to remember. Lo and behold, my gene was normal. There it is. I’m methylating like crazy. I’m loving every single moment of this. And I methylate
with everything: mind, body … mind, mouth and muscle. All three of them. So, I was feeling very, very good. So, I’m going to gift you
with something special. I promised you
that on this hero’s journey, you would be armed with something new. Not just what you already know about: get in there with perseverance
and will power and determination – of course that’s important. But I want to give you epigene-speak. So, you know, getting your veggies. Well, yeah, you already know all that. But now when you
walk into a grocery store, I want you to be highly enlightened. I want you to walk up
to the produce section and say, “I need to score some methyl donors.” (Laughter) I want to be able to find
any way I possibly can to be able to “do” my methyl donors. And you keep saying to yourself,
“Everything I do” from the moment you leave here, what kind of thoughts are you having? Positive thoughts? Loving thoughts? You’re changing your very epigenome. Positive thoughts. Loving thoughts. What are you putting in your mouth? Think about it. Be mindful. What about that physical
movement of yours? Do you actually assume the vertical? I know it’s radical,
but do you assume the vertical? And move! And rejoice that you can do that. Ooh, I love that. The same time, what are you hooked on? What are your genes hooked on? Right? Are you into kicking the fix? Come on!
Who needs this nasty thing. These tall things you spend
$12.50 for at the barista. Ew! Alright? Sugary, fatty, salty, hyperpalatable. It’s just kicking in
with that food addiction, right? No. Instead, come on … Do kale. (Laughter) So, DNA is not destiny! It’s not destiny at all! You are! You write the very script of your life! Mind, mouth and muscle. You’re the ones doing it! Just sitting here right now. You’re writing away. Your histones are busily
monitoring everything in your life. You love that. At the same time, you treat yourself. I always have a cupcake
in at least one slide. There’s always a little treat in there. And you’re also eating and rejoicing with, ahh, whole foods! Love it! Love it! How about that physical activity? We love that too. How about mind-body activity? How about those greens? Ahh … my histones harken. It’s time to methylate. (Laughter) I wish you all a very green
hero’s journey. (Applause)

100 comments on “Epigenetic transformation — you are what your grandparents ate: Pamela Peeke at TEDxLowerEastSide

  1. Ralph Dratman Post author

    Surprisingly good talk that did not get a lot of views (so far). It deserves a bigger audience.

    Reply
  2. Jacob Johnson Post author

    Alan: what is your background? what environmental influences do you consider? As a nurse/midwife… i am very mindful of the influences.

    luences do

    Reply
  3. JUANCARLOS1931 Post author

    Can a bald guy grow new hair pressing the Ctrl Alt Del grow hair again key in the epigenetic keyboard of the mind?

    Reply
  4. SharperSelf Post author

    I was smiling the whole time i watched this video cause now all i learnt in biology and genetics class in premed makes sense in such a wonderful way explained. Thank you!

    Reply
  5. Carlos Flores Post author

    Genetics loads the gun but Epigenetic pulls the trigger. Everyone should watch this!!!! Wish more educators taught like Pamela. Awesome educator/speaker.

    Reply
  6. o 00.0 Post author

    Before Epigenetics there was Dr Pottenger's Cats Studies (and especially his personal notes) of the 1930/40 era where it was shown the disastrous effect of cooked foods, especially through the generations, and the benefit of a natural diet. It seems, today, that the scientists are only now catching-up with Pottenger's findings, some 75 years later! Well done for academe, a brilliant lot!

    Reply
  7. Jeremiah Adams Post author

    So what do you do when you have the Abnormal MTHFR gene mutation, and so eating the Kale won't work, supplements can't be the only way to regene your genes, can it?

    Reply
  8. surfinmuso Post author

    Ah science-it's just like the fashion industry. The hot new thing is "epigenetics" -some new crap that means nothing really-a disposable new theory. Before this it was genes-and the genome project was gonna produce medical miracles-more bullshit. Lies and promises. The irony is that by stating the false assumptions her industry made about DNA-she fails to realise her current topic is the same.

    Reply
  9. surfinmuso Post author

    Talk about over-thinking something to the point of insanity. Here is the diet for everyone everywhere and u don't need to be brainwashed by science bullshit to get it-Eat Food, mostly vegetables and get regular exercise. That is all u need to know.

    Reply
  10. justadartplayer Post author

    seems "A Bridge Too Far" for Epigenetics … don't eat crap you won't get fat, it isn't rocket science or rather Epigenetics 🙂

    Reply
  11. Konrad Skalski Post author

    So I was eating up enough kcal just from veggies and meat , I fuel up myself with methyl donor( or methol not really sure how to spell that) , I exercise 5 times a week for 1 hour and… My weight is around 260 lbs… So I heard that was the solution. What I heard after one year? You need to exercise more in order to lose weight since my diet ( which I was very honest and strict with -> just telling it was just about 1800kcal while my body needs roughly 3000, in theory i should lose 1kg per week without even exercising, but I exercise and my weight is still same!) No, I don't have diabetes and no I don't have thyroid problems. Seem those genetics aren't really where they should be…. I guess… Also you can't sleep much guys, yup… that's true because sleeping transforms sugar ( which you maybe maximum of 10-20g from the veggies) into fat… Holy hell. I can run for 8 miles straight while being as fat I am (nope I have't got any leaner either) So where's my healthy life full of muscles and stuff? Noooooooooooooooooo idea.

    So then what happened? You know where was my problem ? It's not brain, genetic problems etc. I said 'fuck this !' moved on and done what I always felt was right and suddenly I lose 30 lbs in just a month. How? I'VE HAD ENOUGH OF SLEEP which turnt all the sugar I've ate to fat ( which is actually the basic fuel of humans body). My diet was less strict ( i ate around 2000kcal a day, with 4000 once per week) i started to exercise 3 times a week instead of 5 and for 45 mins at home ( sometimes went for a jog). The factor is… stress, the diet and exercise put me on way too big stress on my body which lead problems like metabolism slowing down etc. my advice to you all my friends. Now I am 200 lbs and a lot more lean but not with 6 pack and stuff, but I live a happy and healthy life. Don't put too much stress with yourself, smile, go party, have a drink. Everything is for humans. EVERYTHING. Being happy, getting happier, being loved, feeling someones touch and getting attention of the person you feel are important to you are the biggest recipe to lose weight. If you've read that whole, congratulations. Now don't believe bullshits because" we discovered that !" holy crap they didn't discover that at all, we all knew that for years ( probably around 40 maybe even 50)

    Tip number 2-> let your family know and make them support you, there's nothing more frustrating than the beautiful fried rice meal with even more beautiful fried duck and tons of sauces in front of you but you can't eat it ( With my advice, you can. Once per week but you can) Treat yourself right and have a proper diet that doesn't feel stressful but is healthy. THIS IS THE KEY TO HEALTHIER LIFE !

    Reply
  12. Debbie J. Post author

    If you want to go really deep into Epigenetics then watch you tube videos of Bruce Lipton's
    lectures. And then listen to free Podcasts on iTunes from Mas Sajady. Both of these two will blow your mind and change your life in ways you never dreamed possible. As far as the food goes…you just need to eat organic and stay away from processed GMO foods.
    Learn to read labels and stay away from high fructose corn syrup.

    Reply
  13. Leigh Hope Pfosi Post author

    I say this with a huge smile: take my sense of humor and combine it with your apptitude for the medical sciences [as well as the psychological… and a few more] and the result is —- I learn and laugh and laugh and learn! Thank you for being awesome.

    Reply
  14. Ry The Zoo Guy Post author

    Absolutely hilarious and very eye-opening! She's selling epigenetics very well for an aspiring geneticist 🙂

    Reply
  15. TheSamttatze Post author

    hahaha the way she says things she keeps reminding me of Kassandra – the last pure human – from Dr. Who
    "Methalate me!!! Methalate me!" 😀

    Reply
  16. Aaron Sterling Post author

    the title is only partially right. it's not what your grandparents ate but what they absorb and what you are eating and absorbing.

    Reply
  17. ProdigiousHdawg Post author

    Gosh, if she taught at my school, I would sign up for her class in a heartbeat! I love the way she presents all this important, educational information in such an engaging way, and intertwined with such humor. I really appreciate how she uses more "real person", everyday lingo and explanations and tries to connect with the audience as opposed to just spewing off facts in uber-scietific jargon; she introduces the scientific jargon and then weaves it into stories so we can all understand what's going on. I saw another one of her TED talks, too, and I was equally as enthralled; she really brings science and medicine alive! Bravo! 😀

    Reply
  18. dionysusnow Post author

    Wonderful presentation with great enthusiasm, I would add that DNA is destiny but Multiple destinies are written within.

    Reply
  19. Nelly Coerts Post author

    That story about the hongerwinter, that 2 next generations are skinny is not true. It is probably epigenetics that made sure that we are normal size 😉

    Reply
  20. Dan Lewis Post author

    I wanted to like this speech…but she digresses and wastes time on inconsequentials.
    She gets a thrill out of a seemingly obscene initial set. Sheesh!
    She needed a different speech coach/trainer. The talk, as it is, is too long.

    Reply
  21. Dustin Armogeda Post author

    It still just comes down to "you are what you eat and do". Now that phrase has a new name. Wow, thank you for telling us all something we already knew. She just stretched a five word phrase into a twenty minute Ted talk.

    Reply
  22. Brian Dietrich Post author

    So.. if my grandparents were dairy farmers back in a more natural family farm era, does that explain why I love steak so much? Not a milk drinker though. I do love whey protein, however!

    Reply
  23. Amie Kosberg Post author

    What about diseases like FSH Muscular Dystrophy? My husband cannot grow his muscles back, can he?

    Reply
  24. Manoj Bhaskar Post author

    I just changed DNA damage cell in his mother pregnant and operated damaged DNA Cancer and suger don't get his children his safe lifetime

    Reply
  25. Barbara Latham Post author

    What a terrific presentation! So interesting. I'm sorry for all the candy bars I ate and cigarettes I smoked in my " salad days" because they probably are affecting my grandchildren.

    Reply
  26. Larry Cleveland, RDN, LD, LMT Post author

    Most don’t know that from this information, Merk pharma came out with methyl folate The body have to take off the methyl group before folate gets in the cell. I was surprised to learn this because of the mthfr mutation movement is so strong. Then I learned, even if one has the mutation, taking methylated folate is not necessary. The body is intelligent that it will compensate if enough folate is given it. I have the biochemical pathways to show the science of it. I’m so glad she didn’t go there talking about methylated B vitamin supplements.

    Reply
  27. asubean1 Post author

    Omg. I LOVE her. She is my spirit animal!! Although I was hoping she’d talk about when you have a MTHFR mutation.

    Reply
  28. Prepperjon Post author

    Absolutely the best ted talk I have ever seen!!! I’ve watched several hundred of them and this is the best! Great topic, could have been boring and to complex for anyone under a 165 IQ but NO lol she made it fun and entertaining while teaching and explaining some incredible science. Lots of humour and a little tongue in cheek at times. I’ll be watching this again tomorrow just to see what I may have missed lol. I’ve already hit like and shared with 10 friends. A must see talk lol

    Reply
  29. Rabiyyah Badruddin Post author

    So your genes do not control your destiny, but the proteins in them have a lot more to do with DNA construction and reconstruction! I love this study! A new age is on the horizon, and I'm super excited about it. There's so much that goes into the power of positive thinking. Your Thoughts create Your reality and words rewire your brain.

    Reply
  30. I AM Post author

    hold on a sec, if we are what our grandparents ate… i see a dire future for the grandchildren of todays junkfood junkies.

    Reply
  31. Ed Lewis Post author

    What a bunch of epigenetic BS! Eat some greens, legumes and don’t forget the green tea! They paid this lady (who looks like a foot) to do some metaphysical comedy routine and now she’s a freakin dr guru? please.

    Reply
  32. silkhead44 Post author

    I have the variant in the MTHFR gene…slow methylator…since i found out and corrected nutrients…I'm a new man

    Reply
  33. Bob Owen Post author

    She scratches the surface of the topic she's supposed to be expert in. She should watch more YouTube vids on the topic.

    Reply
  34. Coffeehan Post author

    I really love this woman, I saw her in another TED talk, she makes the listeners engaged and entertained while teaching them at the same time. I wish I could talk publicly like this.

    Reply
  35. Qibili Post author

    This is how education should sound like, happy, crazy fun and mind provoking. Dr. Pam is a star.

    Reply
  36. Kala Nathan Post author

    Interesting how the tree kind of tapers in impact after 3 generations. In Hindu culture, in any ancestral associations used whether when we articulate lineage during weddings or during annual death anniversary of anyone, we always go back to 3 generations.. parent, grandparent and greatgrandparent! Interesting that science now proves that there is actually a scientific connection to that thought process.. method to the madness in proof !

    Not trying to talk about Hinduism, but that connection is one of the first things that popped into my head!
    And the fact that we can alter our destiny by our actions and thoughts ! 🙏

    Reply
  37. Vlad's Rants Post author

    Read15 Minute Manifestation (365-Days 100% Moneyback Guarantee)15 Minute Manifestation (365-Days 100% Moneyback Guaran

    Reply
  38. Vlad's Rants Post author

    This is ted talk Bs. Check dr. Wallach on epigenetics… The death of DNA transmutation , not grandparents genes

    Reply
  39. C. Hudson Post author

    Unless you attain a public criminal record. Then your life- well any life worth living- is over.

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  40. meygaag kabacalaf Post author

    Every dimwit is putting out their crazy theory calling it New!. I don’t listen to none of that !.

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  41. Viki Kása Post author

    I thoroughly enjoyed your speech and learned a lot meanwhile! But when I reached 15:46 and saw gloulash soup (gulyás leves bográcsban), then heared her talking about Hungarians, I was thrilled 😀 Yes, I'm from Hungary. I grew up on foods like this

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  42. coreluminous Post author

    the bit she omits is that war and poverty and oppression which are driven by institutional power systems induce chronic stressors which individuals have no power to ameliorate, and that these stressors are profoundly disruptive to healthy systems, and lead inevitably to stress burdens that become disease states…

    and it is the traumatized gene expression that gets passed down that also afflicts many, many people by settings uo dispositional vulnerabilities.

    the good news is that given a safe psychological, physiological and material support, that admits the health adverse influence of external societal stressors, and thus unburdens the sufferring person by saying 'it's not you, it's you in that socisl setting, as it affects you."

    she ought to have included the ACE study not because of epigenetics alone, but because it tracks the intensity of adverse childhood experiences to various adverse health outcomes down the track.

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